发送询价
生长因子ELISA试剂盒详细介绍：
一.High Sensitivity Human PTH (1-34)ELISA Kit INTENDED USE
This kit is intended for research use only in the determination of human PTH (1-34) in plasma or cell culture media. Reference ranges and clinical utility have not been established.
二.High Sensitivity Human PTH (1-34)ELISA Kit INTRODUCTION
Over the years, studies involving the intermittent dosing of human PTH (1-34) in animals and humans have demonstrated an anabolic effect on bone. This effect was positive for bone mass, size, structure, and strength, demonstrating the antifracture efficacy of the treatment. Recently the FDA has approved the recombinant form of human PTH (1-34) – rhPTH (1-34) or teriparatide, for treatment of many forms of osteoporosis. The measurement of circulating levels of thispeptide/drug may be useful in assessing its pharmacological properties and for appropriate dosing and schedule optimization. Additionally, this assay may be useful in screening samples for both endogenous levels of circulating hPTH (1-34) and elevated levels of this peptide as
it may interfere to varying degrees with 2-site immunometric assays used for measuring intact PTH (1-84).Obtaining precise measurements of human PTH (1-34) are complicated by antibody cross-reactivity to endogenous PTH (1-84),requiring either a pre-assay immunoextraction of PTH (1-84) or assaying for both High Sensitivity Human PTH (1-34)ELISA Kit and intact PTH (1-84) to account for this cross-reactivity.This High Sensitivity (HS) Human PTH (1-34) ELISA Kit uses two antibodies that have been prepared for optimal recognition of human PTH (1-34) while minimizing binding to human PTH (1-84).
We have determined the cross-reactivity of 1-84 to be less than 3% on a molar basis. However, if cross-reactivity correction is desired, the concurrent use of PTH (1-84) standards is suggested.
网址：www.craymeibio.com一.High Sensitivity Human PTH (1-34)ELISA Kit INTENDED USE
This kit is intended for research use only in the determination of human PTH (1-34) in plasma or cell culture media. Reference ranges and clinical utility have not been established.
二.High Sensitivity Human PTH (1-34)ELISA Kit INTRODUCTION
Over the years, studies involving the intermittent dosing of human PTH (1-34) in animals and humans have demonstrated an anabolic effect on bone. This effect was positive for bone mass, size, structure, and strength, demonstrating the antifracture efficacy of the treatment. Recently the FDA has approved the recombinant form of human PTH (1-34) – rhPTH (1-34) or teriparatide, for treatment of many forms of osteoporosis. The measurement of circulating levels of thispeptide/drug may be useful in assessing its pharmacological properties and for appropriate dosing and schedule optimization. Additionally, this assay may be useful in screening samples for both endogenous levels of circulating hPTH (1-34) and elevated levels of this peptide as
it may interfere to varying degrees with 2-site immunometric assays used for measuring intact PTH (1-84).Obtaining precise measurements of human PTH (1-34) are complicated by antibody cross-reactivity to endogenous PTH (1-84),requiring either a pre-assay immunoextraction of PTH (1-84) or assaying for both High Sensitivity Human PTH (1-34)ELISA Kit and intact PTH (1-84) to account for this cross-reactivity.This High Sensitivity (HS) Human PTH (1-34) ELISA Kit uses two antibodies that have been prepared for optimal recognition of human PTH (1-34) while minimizing binding to human PTH (1-84).
We have determined the cross-reactivity of 1-84 to be less than 3% on a molar basis. However, if cross-reactivity correction is desired, the concurrent use of PTH (1-84) standards is suggested.