20ug Recombinant Murine IL-4
2024-04-22 16:56  点击:894
价格:未填
品牌:176
发送询价
重组小鼠IL-4 (Animal Free) 20ug 详细介绍:
中文名称
重组小鼠IL-4 (Animal Free) 20ug 详细介绍:
英文名称
Recombinant Murine IL-4
货号
AF-214-14
试剂级别
细胞培养级
产地
美国PeproTech
别名Synonyms
BCGF, BCDF, B cell stimulating factor (BSF-1)
描述Description
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 120 amino acid residues. Manufactured using all non-animal reagents. 

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