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Human TNFa ELISA KIT Intended use
The Diaclone TNFa ELISA kit is a solid phase sandwich ELISA for the in-vitro qualitative and quantitative determination of TNFa in supernatants, buffered solutions or serum and plasma samples. This assay will recognise both natural and recombinant human TNFa.
This kit has been configured for research only. Not suitable for use in therapeutic procedures.
2. Human TNFa ELISA KIT Introduction
2.1. Summary
Tumor Necrosis Factor (TNFa), also known as cachectin, is a polypeptide cytokine produced by monocytes and macrophages. It functions as a multipotent modulator of immune response and further acts as a potent pyrogen (4, 17). TNFa circulates throughout the body responding to stimuli (infectious agents or tissue injury), activating neutrophils, altering the properties of vascular endothelial cells, regulating metabolic activities of other tissues, as well as exhibiting tumoricidal activity by inducing localized blood clotting. TNFa also inhibits lipoprotein lipase activity resulting in cachexia, a physical wasting condition (4,17). Activation of B-cells by the Epstein Barr virus can be inhibited by TNFa (15). Due to its varied actions throughout the immune system, TNFa may play a role in the pathogenesis of many disease states.
网址：www.craymeibio.com
The Diaclone TNFa ELISA kit is a solid phase sandwich ELISA for the in-vitro qualitative and quantitative determination of TNFa in supernatants, buffered solutions or serum and plasma samples. This assay will recognise both natural and recombinant human TNFa.
This kit has been configured for research only. Not suitable for use in therapeutic procedures.
2. Human TNFa ELISA KIT Introduction
2.1. Summary
Tumor Necrosis Factor (TNFa), also known as cachectin, is a polypeptide cytokine produced by monocytes and macrophages. It functions as a multipotent modulator of immune response and further acts as a potent pyrogen (4, 17). TNFa circulates throughout the body responding to stimuli (infectious agents or tissue injury), activating neutrophils, altering the properties of vascular endothelial cells, regulating metabolic activities of other tissues, as well as exhibiting tumoricidal activity by inducing localized blood clotting. TNFa also inhibits lipoprotein lipase activity resulting in cachexia, a physical wasting condition (4,17). Activation of B-cells by the Epstein Barr virus can be inhibited by TNFa (15). Due to its varied actions throughout the immune system, TNFa may play a role in the pathogenesis of many disease states.
网址：www.craymeibio.com