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骨吸收ELISA试剂盒，Human TRAP 5 ELISA Kit|
产品名称：Human TRAP 5 ELISA Kit
货号：RD197025000 规格：96T 产地：捷克 1. INTENDED USE The RD197025000 Human TRAP 5 Assay is an ImmunoCapture Enzyme-Activity Assay for the quantitative measurement of human TRAP 5 in serum and EDTA plasma. 2.Features · European unio: for in vitro diagnostic use Rest of the world: for research use only! · The total assay time is less than 4 hours · The kit measures TRAP 5 proteins exhibiting enzyme activity in serum and EDTA plasma · Assay format is 96 wells · Quality Controls are recombinant TRAP 5 protein based. No animal sera are used · Calibrators are recombinant protein based · Components of the kit are provided ready to use, concentrated or lyophilized 3. INTRODUCTION TRAP 5 (serum band 5 tartrate-resistant acid phosphatase, TRACP 5; EC 3.1.3.2) is a glycoprotein of 35-37 kDa. TRAP 5 belongs to the most abundant enzymes in osteoclasts. It is expressed in certain differentiated cells of the mononuclear phagocyte system, particularly osteoclasts and alveolar macrophages, where it takes an active part in bone resorption process. High blood levels of TRAP 5 are usually associated with active bone remodelling. Increased serum levels are observed during normal bone growth among healthy children. Elevated serum TRAP levels have been detected in diseases characterized by increased bone resorption; Paget’s disease of the bone, hemodialysis, primary hyperparathyroidism, metastatic malignancies involving bone resorption, multiple myeloma and bilaterally ovariectomized women. Post-menopausal women have higher levels of serum than post-menopausal women on estrogen replacement therapy. Therefore specific determination of TRAP 5 activity can be essential for clinical assessment of bone metabolism. Cross-Reactivity
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温馨提示：丁香通试剂类产品仅用于科学
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