价格:未填
品牌:2094

发送询价

特别提示：包括AR-A014418在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：AR-A014418
英文名称：AR-A014418
产品货号：L10086
产品规格：5mg|10mg|50mg

属性

CAS号	487021-52-3
分子式	C12H12N4O4S
分子量	308.31
熔点	211-213℃
溶解性	DMSO:≥20mg/mL,clear,light yellowH2O:insoluble
存贮条件	储存温度-20℃

描述

产品介绍	AR-A014418是GSK3β选择性抑制剂，IC50为104 nM，对其它26种激酶无明显抑制性。
生化机理	Glycogen synthase kinase 3(GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer′s disease.GSK3 inhibitor,AR-A014418,inhibits GSK3(IC50 = 104 nM),in an ATP-competitive manner(Ki = 38 nM).AR-A014418 does not significantly inhibit cdk2 or cdk5(IC50>100μM) or 26 other kinases,demonstrating high specificity for GSK3.
别名	GSK-3beta抑制剂VIII；N-(4-甲氧基苄基)-N"-(5-硝基-1,3-噻唑-2-基)脲;AR-AO 14418;AR 0133418;AR 014418;GSK 3β inhibitor；N-(4-Methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea

根据您的关注的AR-A014418(487021-52-3)(≥98%)，AR-AO 14418，AR 0133418，N-(4-甲氧基苄基)-N"-(5-硝基-1,3-噻唑-2-基)脲，GSK-3beta抑制剂VIII，N-(4-Methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea，GSK 3β inhibitor，AR 014418，您可能还对以下产品有需求：


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关注AR-A014418(487021-52-3)(≥98%)，AR-AO 14418，AR 0133418，N-(4-甲氧基苄基)-N"-(5-硝基-1,3-噻唑-2-基)脲，GSK-3beta抑制剂VIII，N-(4-Methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea，GSK 3β inhibitor，AR 014418的同时，为您推荐更多您可能感兴趣的产品：

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