FGFR1(P252S) 小鼠单抗
2023-04-16 23:55  点击:132
价格:未填
发送询价
货号:   26254
基因符号:   FGFR1, BFGFR, CD331, CEK, FGFBR, FLG
描述:   Anti-FGFR1(P252S) Mouse Monoclonal Antibody
背景介绍:   The protein FGFR1 is highly conserved between members and throughout evolution. This particular family member of FGFR1 binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations of FGFR1 protein have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome.
免疫原:   A synthetic peptide from the internal region of FGFR1, which includes the mutation of P252S, human origin
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   
ELISA: 1: 1000-1: 2000
WB: 1: 500-1: 1000
IHC: 1: 50-1: 100
浓度:   1 mg/ml
宿主:   Mouse
形式:   Liquid
克隆性:   Monoclonal
亚型:   IgG
纯度:   Purified from ascites
防腐剂: No
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
种属反应性:   Recognizes P252S mutant, but not wild-type FGFR1 of vertebrates
储存条件:    Store at -20°C. Avoid repeated freezing and thawing

蛋白质印迹:   

Western blot analysis of recombinant FGFR1(P252S) and wildtype proteins.

Purified His-tagged FGFR1(P252S) protein (22-376aa, 45KD, lane 2) and corresponding wildtype protein (lane 1) were blotted with Anti-FGFR1(P252S) monoclonal antibody (Cat. #26254).

免疫荧光:   

Immunofluorescence of cells expressing FGFR1 proteins with Anti-FGFR1(P252S) antibody.

HEK293T cells were transfected with pCDNA3-GFP-FGFR1(P252S) plasmid, pCDNA3-GFP-FGFR1 (WT) plasmid, pCDNA3-GFP-FGFR1 (P252R) plasmid or pCDNA3-GFP-FGFR1 (P252T) plasmid, then fixed and stained with Anti-FGFR1(P252S) monoclonal antibody (Cat. #26254).


FGFR1(P252S) 小鼠单抗
FGFR1(P252S) 小鼠单抗
FGFR1(P252S) 小鼠单抗
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